产品简称

~1.0 mg/mL, affinity isolated antibody

NACRES

NA.41

抗体产品类型

primary antibodies

物种反应性

mouse, rat, human

生物来源

rabbit

单抗克隆号

polyclonal

偶连

unconjugated

抗体应用

western blot: 0.5-1.0 μg/mL using rat spinal cord extracts (S1 fraction)

免疫原基因信息

human ... SLC2A1(6513)mouse ... Slc2a1(20525)rat ... Slc2a1(24778)

免疫原蛋白记录号

P11166

外形

solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

应用

Anti-GLUT1 (C-terminal) antibody produced in rabbit has been used in immunoblotting.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

一般描述

Glucose transporter 1 (GLUT1, SLC2A1) belongs to the family of glucose transporters (GLUTs). It is localized to the membrane and is highly expressed in the brain and spinal cord, with a relative high density in the cerebellum. The vascular form of GLUT1 is mainly localized in endothelial cells of blood vessels.

外形

solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

免疫原

peptide corresponding to a sequence at the C-terminus of human GLUT1, conjugated to KLH. The corresponding sequence is identical in rat and mouse GLUT1.

生化/生理作用

GLUT1 is the main glucose transporter in the blood-brain barrier (BBB), which regulates basal glucose levels. Increased expression of GLUT1 is associated with cell growth and in malignant transformation.