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NA.51
acetic acid: 49.00-51.00 mg/mL, clear, colorless
N⁶-甲基-2′-脱氧腺苷已用作标准品,结合超高效液相色谱法和三重四极杆质谱法(UHPLC-QQQ-MS/MS)来测定基因组DNA中的修饰碱基水平。
N⁶-Methyl-2′-deoxyadenosine (N6-Me-dAdo) is a precursor of N⁶-methyl 2′-deoxyadenosine 3′,5′-bisphosphate (N6MABP), a competitive and selective inhibitor of P2Y1 receptors. It is located at the transcription start site and plays a role in increased gene expression in Chlamydomonas reindardtii. N⁶-Me-dAdo augments the within transposable elements and is present at higher levels during the development of Drosophila. It is involved in the regulation of gene transcription, DNA repair, and replication in prokaryotes and protists. N⁶-Me-dAdo complemented with gene bodies might induce gene expression in human cells.
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