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DeepBio得分:5567.2
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是基于文献引用次数，影响因子，文献新近度等因素计算的客观产品评级，得分越高表明该产品经过越可靠的实验验证，质量可信度越高
≥98% (HPLC)
329823846
human ... ERBB2(2064)
DMSO: 20 mg/mL, clear
CP-724714 has been expertly reviewed and recommended by the Chemical Probes Portal. For more information, please visit the CP-724714 probe summary on the Chemical Probes Portal website.
CP724714 is a potent and selective inhibitor of HER2/ErbB2 with an IC₅₀ value of 10 nM. CP724714 is >640-fold selectivity against EGFR, and >1000-fold selective against InsR, IRG-1R, PDGFR, VEGFR2, Abl, Src, c-Met, JNK-2, JNK-3, ZAP-70, CDK-2 and CDK-5 in in vitro kinase assays. CP724714 had antiproliferative effects in a panel of human breast cancer cell lines.
Sold for research purposes under agreement from Pfizer Inc.
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