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The InSolution STAT3 Inhibitor III, WP1066, also referenced under CAS 857064-38-1, controls the biological activity of STAT3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
A 50 mM (5 mg/281 µl) solution of STAT3 Inhibitor III, WP1066 (Cat. No. 573097) in DMSO.
A cell-permeable AG 490 (Cat. No. 658401) tyrphostin analog that acts as an effective STAT3 pathway inhibitor and a much more potent antitumor agent than AG 490 in inhibiting malignant glioma growth both in cultures in vitro (IC₅₀ = 5.6 and 3.7 µM in a viability assay using U87-MG and U373-MG, respectively; no inhibition against nontumor NHA at 10 µM) and in mice in vivo. Shown to cross blood-brain barrier in mice in vivo.
A 50 mM (5 mg/281 µl) solution of STAT3 Inhibitor III, WP1066 (Cat. No. 573097) in DMSO.
Packaged under inert gas
Toxicity: Irritant (B)
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