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affinity isolated antibody, buffered aqueous solution
NA.41
primary antibodies
mouse
rabbit
polyclonal
unconjugated
western blot: suitable using mouse brain lysate
mouse ... Apbb1(11785)
Q9QXJ1
Solution in phosphate buffered saline containing 1.0 mg/mL bovine serum albumin and 0.05% sodium azide.
Anti-Fe65 antibody produced in rabbit is suitable for western blotting using mouse brain lysate.
Solution in phosphate buffered saline containing 1.0 mg/mL bovine serum albumin and 0.05% sodium azide.
synthetic peptide corresponding to amino acid residues 352-369 from mouse Fe65.
Amyloid β A4 precursor protein-binding family B member 1 is a protein encoded by the APBB1 gene in humans and is mapped on human metaphase chromosomes to band 11p15. Fe65 is a neuronal adaptor protein that is involved in brain development, Alzheimer disease amyloid precursor protein (APP) signaling and proteolytic processing of APP. It participates in various processes by recruiting various interacting partners to form functional complexes and acts as a novel regulator of neurite outgrowth. Fe65 significantly alters actin dynamics and mitochondrial function in neuronal cells.
The antibody does not detect endogenous levels of Fe65.
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