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The PKCε Translocation Inhibitor Peptide, Negative Control controls the biological activity of PKCε. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
water: 3 mg/mL
Supplied as a trifluoroacetate salt.
Yedovitzky, M., et al. 1997. J. Biol. Chem. 272, 1417. Johnson, J.A., et al. 1996. J. Biol. Chem.271, 24962.
An octapeptide that selectively inhibits the translocation of protein kinase Cε to subcellular sites in a reversible manner. Inhibition of PKCε translocation is known to specifically block phorbol ester- or norepinephrine-mediated regulation of contraction in cardiomyocytes.
Supplied as a trifluoroacetate salt.
Reversible: yes
H-Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH
Following reconstitution, aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 6 months at -20°C.
Toxicity: Standard Handling (A)
Sold under license of U.S. Patent 5,783,405.
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