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DeepBio得分:5567.2
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≥98% (HPLC), powder
24277709
NA.77
human ... GRIN2B(2904)rat ... Adra1a(29412)
DMSO: 5 mg/mL, clear;H2O: insoluble
NR2B selective NMDA glutamate receptor antagonist which appears to target the \polyamine site\ on the NMDA receptor, setting it apart from other NR2B receptor antagonists. Possesses neuroprotective effects in models of ischemia, but prolongs the QT interval in patients; currently under investigation for acute and chronic pain.
This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
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